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Search Results for " leukotriene a4 "

20

Compounds

Cat No. Product Name Synonyms Targets
T37616 Leukotriene A4 methyl ester Leukotriene A4 methyl ester
Leukotriene A4 methyl ester can be converted into leukotriene C4 monomethyl ester catalyzed by the major alkaline cytosolic glutathione transferase in rat liver, which can be used in metabolism-related studies.
T21696 SC-57461A Aminopeptidase
SC 57461A is a potent and specific leukotriene A4 hydrolase (LTA4H) inhibitor.
TQ0047 DG051 Aminopeptidase
DG051 is a potent leukotriene A4 hydrolase (LTA4H) inhibitor (IC50: 47 nM).
T28698 SC-22716 SC 22716,SC22716 Aminopeptidase
SC-22716 is an orally active leukotriene A4 (LTA4) hydrolase inhibitor.SC-22716 has potential anti-inflammatory activity and may be used in the study of inflammatory bowel disease and psoriasis.
T3715 Acebilustat CTX-4430 Aminopeptidase , LTR
Acebilustat (CTX-4430) (ZK322) is an effective and specific leukotriene B4 hydrolase inhibitor.
T3529 Bestatin hydrochloride Ubenimex hydrochloride Integrin , Aminopeptidase , Antibacterial , Antibiotic
Bestatin hydrochloride (Ubenimex hydrochloride) is an inhibitor of aminopeptidase N (APN)/CD13 and aminopeptidase B.
T6301 Tosedostat CHR-2797 Aminopeptidase , AChR
Tosedostat (CHR-2797) is an orally bioavailable inhibitor of the M1 family of aminopeptidases with potential antineoplastic activity. Tosedostat is converted intracellularly into a poorly membrane-permeable active metabo...
T1257 Bestatin Ubenimex Others , Aminopeptidase , Antibacterial , Antibiotic , LTR
Bestatin (Ubenimex) competitively inhibits many aminopeptidases, including B, N and leucine aminopeptidases. Ubenimex is a microbial metabolite and dipeptide with potential immunomodulatory and antitumor activities. Amin...
T68314 DG-051
DG-051 is a novel leukotriene A4 (LTA4H) hydrolase inhibitor of leukotriene B4 biosynthesis.
T68595 JNJ-26993135
JNJ-26993135 is a potent and selective leukotriene A4 hydrolase (LTA4H) inhibitor.
T19047 PL553 Others
PL553 is a specific and high-affinity fluorogenic substrate of Leukotriene A4 hydrolase (λmax: 210 nm; λem: 410 nm).
T62258 Bestatin trifluoroacetate
Bestatin trifluoroacetate (Ubenimex trifluoroacetate) is a CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase inhibitor that is often used in cancer research.
T25687 Leukotriene C4 LTC4,Leukotriene C
Leukotriene C4 is the conjugation product of Leukotriene A4 and glutathione. It is the major arachidonic acid metabolite in human mast cells, macrophages, and antigen-sensitized lung tissue. It stimulates mucus secretion...
T40826 5(S)​-​HPETE
5(S)-Hydroperoxyeicosatetraenoic acid (5(S)-HpETE) is a monohydroperoxy polyunsaturated fatty acid (PUFA) generated by the enzymatic conversion of arachidonic acid via 5-lipoxygenase (5-LO). Subsequently, 5(S)-HpETE unde...
T9690 LTA4H-IN-1 LYS-006
LTA4H-IN-1 is a potent inhibitor of leukotriene A4 hydrolase (LTA4H) with an IC 50 of 2 nM. LTA4H-IN-1 can be used for the research of inflammatory and autoimmune disorders [1].
T37652 5(S),6(R)-DiHETE
5(S),6(R)-DiHETE is a dihydroxy polyunsaturated fatty acid and a nonenzymatic hydrolysis product of leukotriene A4 (LTA4). Mouse liver cytosolic epoxide hydrolase catalyzes the conversion of LTA4 to 5(S),6(R)-DiHETE. It ...
T36051 Lipoxin A4 LXA4
Lipoxin A4 (LXA4) is a trihydroxy fatty acid containing a conjugated tetraene, produced by the metabolism of (±)15-HETE or 15-HpETE with human leukocytes.[1] LXA4 is equipotent to leukotriene B4 in inducing superoxide g...
T36052 Lipoxin A4 methyl ester LXA4 methyl ester
Lipoxin A4 methyl ester (LXA4 methyl ester) is a more lipid soluble, prodrug formulation of the transcellular metabolite LXA4. LXA4 is a trihydroxy fatty acid containing a conjugated tetraene, produced by the metabolism ...
T35943 15(S)-HpETE
15(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 15-lipoxygenase (15-LO) on arachidonic acid. It is either metabolized to 14,15-leukotriene A4 [1] or reduced to 15(S)-HETE by ...
T37970 12-epi Leukotriene B4 12-epi Leukotriene B4
Leukotriene B4 (LTB4) compounds are produced by both enzymatic and non-enzymatic processes. The products of enzymatic origin, via Leukotriene A4 (LTA4) hydrolase, are stereospecifically 12(R). Non-enzymatic hydrolysis pr...
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