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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T37616 | Leukotriene A4 methyl ester | Leukotriene A4 methyl ester | |
Leukotriene A4 methyl ester can be converted into leukotriene C4 monomethyl ester catalyzed by the major alkaline cytosolic glutathione transferase in rat liver, which can be used in metabolism-related studies. | |||
T21696 | SC-57461A | Aminopeptidase | |
SC 57461A is a potent and specific leukotriene A4 hydrolase (LTA4H) inhibitor. | |||
TQ0047 | DG051 | Aminopeptidase | |
DG051 is a potent leukotriene A4 hydrolase (LTA4H) inhibitor (IC50: 47 nM). | |||
T28698 | SC-22716 | SC 22716,SC22716 | Aminopeptidase |
SC-22716 is an orally active leukotriene A4 (LTA4) hydrolase inhibitor.SC-22716 has potential anti-inflammatory activity and may be used in the study of inflammatory bowel disease and psoriasis. | |||
T3715 | Acebilustat | CTX-4430 | Aminopeptidase , LTR |
Acebilustat (CTX-4430) (ZK322) is an effective and specific leukotriene B4 hydrolase inhibitor. | |||
T3529 | Bestatin hydrochloride | Ubenimex hydrochloride | Integrin , Aminopeptidase , Antibacterial , Antibiotic |
Bestatin hydrochloride (Ubenimex hydrochloride) is an inhibitor of aminopeptidase N (APN)/CD13 and aminopeptidase B. | |||
T6301 | Tosedostat | CHR-2797 | Aminopeptidase , AChR |
Tosedostat (CHR-2797) is an orally bioavailable inhibitor of the M1 family of aminopeptidases with potential antineoplastic activity. Tosedostat is converted intracellularly into a poorly membrane-permeable active metabo... | |||
T1257 | Bestatin | Ubenimex | Others , Aminopeptidase , Antibacterial , Antibiotic , LTR |
Bestatin (Ubenimex) competitively inhibits many aminopeptidases, including B, N and leucine aminopeptidases. Ubenimex is a microbial metabolite and dipeptide with potential immunomodulatory and antitumor activities. Amin... | |||
T68314 | DG-051 | ||
DG-051 is a novel leukotriene A4 (LTA4H) hydrolase inhibitor of leukotriene B4 biosynthesis. | |||
T68595 | JNJ-26993135 | ||
JNJ-26993135 is a potent and selective leukotriene A4 hydrolase (LTA4H) inhibitor. | |||
T19047 | PL553 | Others | |
PL553 is a specific and high-affinity fluorogenic substrate of Leukotriene A4 hydrolase (λmax: 210 nm; λem: 410 nm). | |||
T62258 | Bestatin trifluoroacetate | ||
Bestatin trifluoroacetate (Ubenimex trifluoroacetate) is a CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase inhibitor that is often used in cancer research. | |||
T25687 | Leukotriene C4 | LTC4,Leukotriene C | |
Leukotriene C4 is the conjugation product of Leukotriene A4 and glutathione. It is the major arachidonic acid metabolite in human mast cells, macrophages, and antigen-sensitized lung tissue. It stimulates mucus secretion... | |||
T40826 | 5(S)-HPETE | ||
5(S)-Hydroperoxyeicosatetraenoic acid (5(S)-HpETE) is a monohydroperoxy polyunsaturated fatty acid (PUFA) generated by the enzymatic conversion of arachidonic acid via 5-lipoxygenase (5-LO). Subsequently, 5(S)-HpETE unde... | |||
T9690 | LTA4H-IN-1 | LYS-006 | |
LTA4H-IN-1 is a potent inhibitor of leukotriene A4 hydrolase (LTA4H) with an IC 50 of 2 nM. LTA4H-IN-1 can be used for the research of inflammatory and autoimmune disorders [1]. | |||
T37652 | 5(S),6(R)-DiHETE | ||
5(S),6(R)-DiHETE is a dihydroxy polyunsaturated fatty acid and a nonenzymatic hydrolysis product of leukotriene A4 (LTA4). Mouse liver cytosolic epoxide hydrolase catalyzes the conversion of LTA4 to 5(S),6(R)-DiHETE. It ... | |||
T36051 | Lipoxin A4 | LXA4 | |
Lipoxin A4 (LXA4) is a trihydroxy fatty acid containing a conjugated tetraene, produced by the metabolism of (±)15-HETE or 15-HpETE with human leukocytes.[1] LXA4 is equipotent to leukotriene B4 in inducing superoxide g... | |||
T36052 | Lipoxin A4 methyl ester | LXA4 methyl ester | |
Lipoxin A4 methyl ester (LXA4 methyl ester) is a more lipid soluble, prodrug formulation of the transcellular metabolite LXA4. LXA4 is a trihydroxy fatty acid containing a conjugated tetraene, produced by the metabolism ... | |||
T35943 | 15(S)-HpETE | ||
15(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 15-lipoxygenase (15-LO) on arachidonic acid. It is either metabolized to 14,15-leukotriene A4 [1] or reduced to 15(S)-HETE by ... | |||
T37970 | 12-epi Leukotriene B4 | 12-epi Leukotriene B4 | |
Leukotriene B4 (LTB4) compounds are produced by both enzymatic and non-enzymatic processes. The products of enzymatic origin, via Leukotriene A4 (LTA4) hydrolase, are stereospecifically 12(R). Non-enzymatic hydrolysis pr... |